
Without enough ADH being released from the posterior pituitary gland, the kidneys are not getting the signal to reabsorb water. Neurogenic diabetes insipidus happens when there is some kind of trauma or tumor in the hypothalamus or pituitary gland which is causing insufficient ADH to be released. Pathophysiology Neurogenic diabetes insipidus The word insipidus comes from Latin meaning “tasteless,” referring to the diluteness of the urine. The word diabetes comes from Latin and Greek meaning “siphon” or “to pass through,” referring to excessive urination common with the disease. Dilute the blood so the blood osmolarity drops to a normal levelĭiabetes insipidus is sometimes jokingly called “the other diabetes,” meaning it’s not related to the much more common diabetes mellitus.If the body senses any of these three things, it will release ADH from the posterior pituitary gland, which will cause the kidneys to reabsorb more water, which helps to: Hypernatremia (increased blood osmolarity).Antidiuretic hormone reviewĪs a quick overview, ADH is released by the posterior pituitary gland in response to: If you would like more in-depth information about ADH, we gave an overview of ADH in the pathophysiology section of this playlist. With diabetes insipidus, the body has too little antidiuretic hormone (ADH), and with SIADH, the body has too much ADH. Water absorption shall not be more than 0.6 per unit by weight.What is the difference between SIADH and DI? The specific gravity of aggregates normally used in road construction ranges from about 2.5 to 3.0 with an average of about 2.68. Recommended Values of Specific Gravity and Water Absorption for Aggregates ** Though high specific gravity is considered as an indication of high strength, it is not possible to judge the suitability of a sample aggregate without finding the mechanical properties such as aggregate crushing, impact and abrasion values. (3) Water Absorption = (( W 3 – W 4) / W 4 ) X 100 ** The size of the aggregate and whether it has been artificially heated should be indicated. (2) Apparent specific gravity = W 4/ ( W 4– ( W 1 1– W 2)) (1) Specific gravity = W 3 / ( W 3– ( W 1– W 2))

Weight of water equal to the volume of the aggregate = W 3–( W 1– W 2 )g Formulas: Weight of saturated aggregate in water = W 1 – W 2 g Weight of saturated surface dry aggregate in air = W 3g

Weight of basket suspended in water = W 2 g Weight of saturated aggregate suspended in water with basket = W 1g It is then removed from the oven, cooled in an air tight container and weighted= W 4 g.


An air tight container of capacity similar to that of the basket.A container for filling water and suspending the basket.A wire basket of not more than 6.3 mm mesh or a perforated container of convenient size with thin wire hangers for suspending it from the balance.A thermostatically controlled oven to maintain temperature at 100-110° C.A balance of capacity about 3kg, to weigh accurate 0.5g, and of such a type and shape as to permit weighing of the sample container when suspended in water.Apparatus for testing Specific Gravity and Water Absorption of Aggregates Apparatus Required
